When was mesothelioma first described?
Mesothelioma was first described in 1907 by the Austrian surgeon Julius Maggi. He named it after the Greek word for membrane, “mesos” and the Latin word for the lung, “tela”. A mesothelioma is a rare form of cancer that affects the mesothelium, or membrane that covers the organs. Mesothelium consists of many layers of tissue that surround the lungs and heart and protect them from infections. Typically, mesothelioma is diagnosed when the cancer is in an advanced stage and has spread to other organs. Mesothelioma can affect the pleura, heart, gastrointestinal tract, or pericardium.
What is canine mesothelioma?
Mesothelioma is cancer that originates in the mesothelial cells. The mesothelium is the thin layer of tissue that lines the cavity between the chest (pleura) and abdomen (peritoneum). It includes the heart, lungs, and the spaces in between. A mesothelioma is a rare form of cancer that affects dogs. It is a type of cancer that is caused by the long-term inhalation of asbestos fibers. Mesothelioma is not contagious, but the dog may die before a diagnosis can be made.
Canine mesothelioma treatment
Surgery process for canine mesothelioma?
The most important thing to remember is that the surgery will be performed under general anesthesia and your dog will be in a controlled environment with medical personnel. The veterinarian will remove the large intestine, small intestine, and spleen. The veterinarian will also remove the pancreas and part of the stomach. The veterinarian will take tissue samples for testing. The veterinarian may need to make a small incision on his/her own body to remove the tumor. The veterinarian will remove the tumor and the intestinal lining. The veterinarian will then suture up the wound and treat it with antibiotics.
Chemotherapy drugs used to treat canine mesothelioma
What are the side effects?
The chemotherapy drugs used to treat mesothelioma are called alkylating agents. The alkylating agents are very toxic to the dog’s cells and cause damage to the DNA of the cells. The side effects can be mild, moderate, or severe depending on the type of chemotherapy used, how much is given at one time, and how old the dog is. The mild side effects include:
- Loss of appetite
Side effects of Chemotherapy drugs
Potential negative side effects can include:
- Increased heart rate and blood pressure. These are usually mild but can be severe. The goal is to keep these from becoming a problem.
- Bone marrow suppression may cause anemia (low red blood cell count) and weakness. These are usually mild but can be severe.
- Nausea and vomiting can be severe.
- Weight loss is common when the dog is being treated with chemotherapy.
- Muscle pain, especially in the back and legs.
- Loss of appetite can be severe if the dog is given chemotherapy at a high dose or is very old.
- Weakness, which can be severe if the dog is very old or has been treated with chemotherapy at a high dose.
Radiation therapy for canine mesothelioma
Radiation therapy is a treatment option for dogs with malignant mesothelioma. Radiation therapy is a type of chemotherapy that uses high-energy radiation to destroy cancer cells. Radiation therapy works in several ways. The high-energy radiation destroys the cancer cells by damaging the DNA inside the cell.
Radiation therapy also shrinks the tumor by destroying the connective tissue which holds the cancer cells together. Radiation therapy is used in dogs that have had surgery to remove malignant mesothelioma, or in dogs that have had chemotherapy and do not respond to treatment.
The prognosis for a dog with mesothelioma
Canine mesothelioma – what is the prognosis? What are the chances of my dog’s survival with this type of cancer?
How can I help my dog at home? How can I help my dog at home?
Dogs with mesothelioma can be successfully treated like any other type of cancer. Your veterinarian will provide the best treatment options for your dog and its unique needs. Dogs face a poor prognosis if they are not treated early enough. Early diagnosis and treatment can improve the chances of survival.
Is surgery the only option for treating canine mesothelioma?
No. There are several non-surgical options available including chemotherapy, radiation therapy, and immunotherapy. Ask the veterinarian. Canine mesothelioma is a very aggressive cancer and dogs with this type of cancer face a poor prognosis if they are not treated early enough. Early diagnosis and treatment can improve the chances of survival.